Daratumumab (Darzalex)

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Mechanism of action

Monoclonal antibody directed against CD38, which is expressed on Multiple myeloma cells.

Preliminary data

Multiple myeloma

  1. Abstract: Plesner, Torben, Lokhorst, Henk, Gimsing, Peter, Nahi, Hareth, Lisby, Steen, Richardson, Paul G. Daratumumab, a CD38 Monoclonal Antibody in Patients with Multiple Myeloma - Data From a Dose-Escalation Phase I/II Study. ASH Annual Meeting Abstracts 2012 120: 73 link to abstract
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