Duvelisib (Copiktra)

Mechanism of action

PI3K-δ,γ inhibitor

Preliminary data

Chronic lymphocytic leukemia

1. Abstract: Manish Patel, Brad S. Kahl, Steven M. Horwitz, Francine M. Foss, Yasuhiro Oki, Pierluigi Porcu, Jennifer Sweeney, Kerstin Allen, Kerrie Faia, Patricia Harris, Joi Dunbar, Howard M. Stern, Patrick Kelly, Susan O'Brien. Preliminary Safety and Efficacy Of IPI-145, a Potent Inhibitor Of Phosphoinositide-3-Kinase-δ,γ, In Patients With Chronic Lymphocytic Leukemia. Blood Nov 2013,122(21)677 link to original abstract