Category:PI3K gamma inhibitors

From Wikipedia: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells.