Factor VIIa, recombinant (NovoSeven RT)
Also known as coagulation factor VIIa, factor 7a, NovoSeven, Novo-Seven, or NovoSeven room temperature stable.
General information
Class/mechanism: Recombinant factor VIIa; complexes with tissue factor and can activate coagulation factors X to Xa and IX to IXa, which results in conversion of prothrombin to thrombin, and fibrinogen to fibrin to form a fibrin clot. There is still uncertainty about the precise mechanism, and activation of factor X on platelet surfaces may also play an important role. Clinical applications include use for patients with inhibitors to factors VIII and IX, as can be the case in hemophilia A and hemophilia B.[1][2][3]
Route: IV
Extravasation: no information
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