Thrombocytosis
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Definition
Platelet count greater than or equal to 450 × 109/L (local reference ranges may vary).[1]
Initial evaluation
May consist of:
- CBC with differential
- Iron, total iron binding capacity (TIBC), ferritin
- JAK2 V617F mutation
- CALR exon 9 indels
- MPL exon 10 mutations
- Peripheral smear
- Clinical history (e.g. recent surgery or other reasons for reactive thrombocytosis), lifestyle factors
References
- ↑ Elisa Rumi and Mario Cazzola. How I treat essential thrombocythemia. Blood 2016 128:2403-2414. PubMed