Tropisetron (Navoban)

Mechanism of action

From NCI: "An indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy-and radiotherapy-induced nausea and vomiting."

History of FDA approval

Not FDA-approved; available in several countries

Also known as

ICS 205-930, Setrovel