Fruquintinib (Elunate)

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Mechanism of action

VEGFR inhibitor

Diseases for which it is used

History of changes in NMPA indication

  • 2018-09: Approved for the treatment of patients with metastatic colorectal cancer (CRC) who have been previously treated with fluoropyrimidine, oxaliplatin and irinotecan, including those who have previously received anti-VEGF therapy and/or anti-epidermal growth factor receptor (EGFR) therapy (RAS wild type). (Based on FRESCO)

Also known as

  • Code name: HMPL-013
  • Brand name: Elunate