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Steroid
|
Equivalent dose (mg)
|
Half-life (hours), biologic
|
Relative anti-inflammatory (glucocorticoid) potency
|
Relative mineralocorticoid (Na+ retaining) potency
|
Cortisone
|
25
|
8-12
|
0.8
|
0.8
|
Hydrocortisone
|
20
|
8-12
|
1
|
1
|
Prednisone
|
5
|
18-36
|
4
|
0.8
|
Prednisolone
|
5
|
18-36
|
4
|
0.8
|
Methylprednisolone (Solu-Medrol)
|
4
|
18-36
|
5
|
0.5
|
Dexamethasone (Decadron)
|
0.75
|
36-54
|
25
|
0
|
References
- Meikle AW, Tyler FH. Potency and duration of action of glucocorticoids. Effects of hydrocortisone, prednisone and dexamethasone on human pituitary-adrenal function. Am J Med. 1977 Aug;63(2):200-7. PubMed