Difference between revisions of "Leucovorin (Folinic acid)"

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(Created page with "==General information== Class/mechanism: <ref name="insert">[http://patient.cancerconsultants.com/druginserts/Leucovorin_inj.pdf Folinic acid (Leucovorin) package insert]</ref><r...")
 
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==General information==
 
==General information==
Class/mechanism: <ref name="insert">[http://patient.cancerconsultants.com/druginserts/Leucovorin_inj.pdf Folinic acid (Leucovorin) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/folinicacid.pdf Folinic acid (Leucovorin) package insert (locally hosted backup)]</ref>
+
Class/mechanism: Folic acid analog; counteracts the effects of folic acid antagonists such as methotrexate, which acts by inhibiting dihydrofolate reductase.<ref name="insert">[http://patient.cancerconsultants.com/druginserts/Leucovorin_inj.pdf Folinic acid (Leucovorin) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/folinicacid.pdf Folinic acid (Leucovorin) package insert (locally hosted backup)]</ref>
<br>Route: TBD
+
<br>Route: PO, IM, IV
<br>Extravasation: TBD
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<br>Extravasation: no information
  
 
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer.  Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the package insert<ref name="insert"></ref>.  
 
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer.  Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the package insert<ref name="insert"></ref>.  
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==Patient drug information==
 
==Patient drug information==
 
*[http://chemocare.com/bio/folinic_acid.asp Folinic acid (Leucovorin) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/folinic_acid.asp Folinic acid (Leucovorin) patient drug information (Chemocare)]</ref>
 
*[http://chemocare.com/bio/folinic_acid.asp Folinic acid (Leucovorin) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/folinic_acid.asp Folinic acid (Leucovorin) patient drug information (Chemocare)]</ref>
*[http://www.uptodate.com/contents/folinicacid-patient-drug-information Folinic acid (Leucovorin) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/folinicacid-patient-drug-information Folinic acid (Leucovorin) patient drug information (UpToDate)]</ref>
+
*[http://www.uptodate.com/contents/leucovorin-patient-drug-information Folinic acid (Leucovorin) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/leucovorin-patient-drug-information Folinic acid (Leucovorin) patient drug information (UpToDate)]</ref>
  
 
==References==
 
==References==
 
<references/>
 
<references/>

Revision as of 02:38, 16 January 2012

General information

Class/mechanism: Folic acid analog; counteracts the effects of folic acid antagonists such as methotrexate, which acts by inhibiting dihydrofolate reductase.[1][2]
Route: PO, IM, IV
Extravasation: no information

For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the package insert[1].

Patient drug information

References