Difference between revisions of "Sapacitabine (CS-682)"

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==Preliminary results==
 
==Preliminary results==
 
===[[Acute myeloid leukemia]]===
 
===[[Acute myeloid leukemia]]===
# '''CYC682-06:''' Kantarjian H, Faderl S, Garcia-Manero G, Luger S, Venugopal P, Maness L, Wetzler M, Coutre S, Stock W, Claxton D, Goldberg SL, Arellano M, Strickland SA, Seiter K, Schiller G, Jabbour E, Chiao J, Plunkett W. Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study. Lancet Oncol. 2012 Nov;13(11):1096-104. Epub 2012 Oct 15. [https://doi.org/10.1016/S1470-2045(12)70436-9 link to original article] [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004358/ link to PMC article] [https://pubmed.ncbi.nlm.nih.gov/23075701/ PubMed] [https://clinicaltrials.gov/study/NCT00590187 Clinical Trials Registry]
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# '''CYC682-06:''' Kantarjian H, Faderl S, Garcia-Manero G, Luger S, Venugopal P, Maness L, Wetzler M, Coutre S, Stock W, Claxton D, Goldberg SL, Arellano M, Strickland SA, Seiter K, Schiller G, Jabbour E, Chiao J, Plunkett W. Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study. Lancet Oncol. 2012 Nov;13(11):1096-104. Epub 2012 Oct 15. [https://doi.org/10.1016/S1470-2045(12)70436-9 link to original article] [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004358/ link to PMC article] [https://pubmed.ncbi.nlm.nih.gov/23075701/ PubMed] [https://clinicaltrials.gov/study/NCT00590187 NCT00590187]
  
 
==Also known as==
 
==Also known as==

Revision as of 21:24, 4 July 2023

Mechanism of action

Pyrimidine analogue

Preliminary results

Acute myeloid leukemia

  1. CYC682-06: Kantarjian H, Faderl S, Garcia-Manero G, Luger S, Venugopal P, Maness L, Wetzler M, Coutre S, Stock W, Claxton D, Goldberg SL, Arellano M, Strickland SA, Seiter K, Schiller G, Jabbour E, Chiao J, Plunkett W. Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study. Lancet Oncol. 2012 Nov;13(11):1096-104. Epub 2012 Oct 15. link to original article link to PMC article PubMed NCT00590187

Also known as

  • Code name: CS-682