Difference between revisions of "Agatolimod (PF-3512676)"
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Revision as of 00:44, 3 December 2022
Mechanism of action
From the NCI Drug Dictionary: The tricosasodium salt of a synthetic 24-mer oligonucleotide containing 3 CpG motifs with potential antineoplastic and immunostimulatory activity. Agatolimod selectively targets Toll-like receptor 9 (TLR9), thereby activating dendritic and B cells and stimulating cytotoxic T cell and antibody responses against tumor cells bearing tumor antigens.