Difference between revisions of "Cytarabine liposomal (DepoCyt)"
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*[http://chemocare.com/bio/cytarabine_liposomal.asp Cytarabine liposomal (DepoCyt) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/cytarabine_liposomal.asp Cytarabine liposomal (DepoCyt) patient drug information (Chemocare)]</ref> | *[http://chemocare.com/bio/cytarabine_liposomal.asp Cytarabine liposomal (DepoCyt) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/cytarabine_liposomal.asp Cytarabine liposomal (DepoCyt) patient drug information (Chemocare)]</ref> | ||
*[http://www.uptodate.com/contents/liposomal-cytarabine-patient-drug-information Cytarabine liposomal (DepoCyt) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/liposomal-cytarabine-patient-drug-information Cytarabine liposomal (DepoCyt) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/liposomal-cytarabine-patient-drug-information Cytarabine liposomal (DepoCyt) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/liposomal-cytarabine-patient-drug-information Cytarabine liposomal (DepoCyt) patient drug information (UpToDate)]</ref> | ||
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Revision as of 03:13, 24 December 2011
General information
Class/mechanism: Pyrimidine analog, mimics cytosine. Converted intracellularly into cytarabine-5-triphosphate (ara-CTP). Exact mechanism of action not known; believed to inhibit DNA polymerase, incorporate into DNA and RNA, and kill cells undergoing DNA synthesis (S-phase) and sometimes block cells from progressing from the G1 phase to the S-phase.[1][2]
Route: IT
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the package insert[1].
Patient drug information
- Cytarabine liposomal (DepoCyt) patient drug information (Chemocare)[3]
- Cytarabine liposomal (DepoCyt) patient drug information (UpToDate)[4]