Difference between revisions of "Afuresertib (GSK-2110183)"
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Revision as of 03:33, 16 November 2014
Mechanism of action
Oral AKT1 inhibitor
Preliminary results
Multiple myeloma
- Spencer A, Yoon SS, Harrison SJ, Morris SR, Smith DA, Brigandi RA, Gauvin J, Kumar R, Opalinska JB, Chen C. The novel AKT inhibitor afuresertib shows favorable safety, pharmacokinetics, and clinical activity in multiple myeloma. Blood. 2014 Oct 2;124(14):2190-5. Epub 2014 Jul 29. link to original article PubMed