Difference between revisions of "Zidovudine (Retrovir)"
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Warner-admin (talk | contribs) m (Text replacement - "Adult T-cell leukemia/lymphoma" to "Adult T-cell leukemia-lymphoma") |
Warner-admin (talk | contribs) m (Text replacement - "[[Category:Adult T-cell leukemia/lymphoma" to "[[Category:Adult T-cell leukemia-lymphoma") |
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Revision as of 16:23, 23 November 2019
Mechanism of action
From the NCI Drug Dictionary: A synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyrimidines.
Diseases for which it is used
Also known as
- Generic names: azidothymidine, AZT, ZDV
- Brand names: Aztec, Retrovir