Difference between revisions of "Cetuximab (Erbitux)"
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==Patient drug information== | ==Patient drug information== | ||
| + | *[http://chemocare.com/bio/cetuximab.asp Cetuximab (Erbitux) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/cetuximab.asp Cetuximab (Erbitux) patient drug information (Chemocare)]</ref> | ||
*[http://www.uptodate.com/contents/cetuximab-patient-drug-information Cetuximab (Erbitux) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/cetuximab-patient-drug-information Cetuximab (Erbitux) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/cetuximab-patient-drug-information Cetuximab (Erbitux) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/cetuximab-patient-drug-information Cetuximab (Erbitux) patient drug information (UpToDate)]</ref> | ||
Revision as of 19:01, 5 December 2011
General information
Class/mechanism: EGFR antagonist; monoclonal antibody that binds to the EGFR/HER1/c-ErbB-1 receptor tyrosine kinase, competitively inhibiting binding of epidermal growth factor (EGF) and other ligands, such as transforming growth factor-alpha. This results in inhibition of cell growth, induction of apoptosis, decreased matrix metalloproteinase, and decreased vascular endothelial growth factor production.[1][2]
Route: IV
Extravasation: no information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the package insert[1].
Patient drug information
- Cetuximab (Erbitux) patient drug information (Chemocare)[3]
- Cetuximab (Erbitux) patient drug information (UpToDate)[4]
Regimens
Standard format will be:
<acronym (if any)> <generic drug1, generic drug2, generic drug3, etc.> (disease)