Difference between revisions of "Copanlisib (Aliqopa)"
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| − | == | + | ==General information== |
| − | From [http://www.cancer.gov/drugdictionary?CdrID=653981 NCI Drug Dictionary]: A phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. Copanlisib inhibits the activation of the PI3K signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. | + | Class/mechanism: From [http://www.cancer.gov/drugdictionary?CdrID=653981 NCI Drug Dictionary]: A phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. Copanlisib inhibits the activation of the PI3K signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations.<ref name="insert">[http://labeling.bayerhealthcare.com/html/products/pi/Aliqopa_PI.pdf Copanlisib (Aliqopa) package insert]</ref><ref>[[Media:Copanlisib.pdf | Copanlisib (Aliqopa) package insert (locally hosted backup)]]</ref><ref>[http://aliqopa.com Aliqopa manufacturer's website]</ref> |
| + | <br>Route: PO | ||
| + | <br>Extravasation: n/a | ||
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| + | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://reference.medscape.com/drug/zytiga-abiraterone-999651 Medscape], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> | ||
==Diseases for which it is used== | ==Diseases for which it is used== | ||
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*'''Code name:''' BAY 80-6946 | *'''Code name:''' BAY 80-6946 | ||
*'''Brand name:''' Aliqopa | *'''Brand name:''' Aliqopa | ||
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| + | ==References== | ||
| + | <references/> | ||
[[Category:Drug index]] | [[Category:Drug index]] | ||
Revision as of 07:11, 21 May 2018
General information
Class/mechanism: From NCI Drug Dictionary: A phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. Copanlisib inhibits the activation of the PI3K signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations.[1][2][3]
Route: PO
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, Medscape, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
History of changes in FDA indication
- 9/14/2017: Granted FDA accelerated approval "for the treatment of adult patients with relapsed follicular lymphoma who have received at least two prior systemic therapies."
Also known as
- Code name: BAY 80-6946
- Brand name: Aliqopa