Difference between revisions of "Eosinophilia"

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*CBC with differential
 
*CBC with differential
 
*Comprehensive metabolic panel (CMP)
 
*Comprehensive metabolic panel (CMP)
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*Peripheral smear
 
*Vitamin B12  
 
*Vitamin B12  
 
*Troponin I
 
*Troponin I
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*T-Cell Receptor Gene Rearrangement PCR.  
 
*T-Cell Receptor Gene Rearrangement PCR.  
 
*BCR-ABL FISH
 
*BCR-ABL FISH
*Stool ova and parisites
+
*Immunoglobulins IgG, IgA, IgM
 +
*Cortisol
 +
*HIV, HTLV-I, HTLV-II serologies
 +
*Serum tryptase
 +
*Stool ova and parasites
 
*Chest x-ray  
 
*Chest x-ray  
 
*Echocardiogram
 
*Echocardiogram

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Definition

  • Mild eosinophilia: Absolute eosinophil count 500 to 1500 cells/uL
  • Moderate eosinophilia: Absolute eosinophil count 1500 to 5000 cells/uL
  • Severe eosinophilia: Absolute eosinophil count >5000 cells/uL

Evaluation

May consist of:

  • CBC with differential
  • Comprehensive metabolic panel (CMP)
  • Peripheral smear
  • Vitamin B12
  • Troponin I
  • CK
  • Strongyloides Antibody
  • CHIC2, 4q12 Deletion (FIP1L1 and PDGFRA Fusion) FISH.
  • T-Cell Receptor Gene Rearrangement PCR.
  • BCR-ABL FISH
  • Immunoglobulins IgG, IgA, IgM
  • Cortisol
  • HIV, HTLV-I, HTLV-II serologies
  • Serum tryptase
  • Stool ova and parasites
  • Chest x-ray
  • Echocardiogram
  • CT scans to evaluate for pulmonary pathology, lymphadenopathy
  • Bone marrow biopsy
  • Pulmonary function tests (PFTs)
  • Clinical/infection history, international travel
  • Medications