Difference between revisions of "Neutropenia & leukopenia"
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==Definition== | ==Definition== | ||
Revision as of 16:42, 11 December 2017
Use of this site is subject to you reading and agreeing with the terms set forth in the disclaimer. If this is your first time visiting, we suggest you read the tutorial.
Definition
- Mild neutropenia: ANC (absolute neutrophil count) 1000 to 1500 cells/uL
- Moderate neutropenia: ANC 500 to <1000 cells/uL
- Severe neutropenia: ANC <500 cells/uL
Evaluation
May consist of:
- CBC with differential
- Basic metabolic panel (BMP)
- Reticulocyte count
- Vitamin B12
- Folic acid
- Copper
- Urinalysis
- LDH
- Uric acid
- C3, C4
- ANA, anti-DNA antibody
- Peripheral blood flow cytometry
- Peripheral smear
- Clinical/infection history, autoimmune/rheumatologic disease, lifestyle factors (e.g. alcohol)
- Medications
- Check for splenomegaly and lymphadenopathy
- Bone marrow biopsy