Difference between revisions of "Pixantrone (Pixuvri)"
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==Also known as== | ==Also known as== | ||
| − | BBR 2778 | + | *'''Code name:''' BBR 2778 |
| + | *'''Generic name:''' pixantrone dimaleate | ||
| + | *'''Brand name:''' Pixuvri | ||
[[Category:Drug index]] | [[Category:Drug index]] | ||
| − | |||
[[Category:Intravenous medications]] | [[Category:Intravenous medications]] | ||
Revision as of 01:24, 30 November 2017
Although this drug is EMA approved as of 5/31/2013, it is not yet FDA approved.
Mechanism of action
From the NCI Drug Dictionary: The dimaleate salt of a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Route: IV
Diseases for which it is used
Also known as
- Code name: BBR 2778
- Generic name: pixantrone dimaleate
- Brand name: Pixuvri