Difference between revisions of "Chidamide (Epidaza)"

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(Created page with "==Mechanism of action== HDAC inhibitor ==Preliminary data== ===Peripheral T-cell lymphoma=== # Shi Y, Dong M, Hong X, Zhang W, Feng J, Zhu J, Yu L, Ke X, Huang H, Shen Z,...")
 
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==Preliminary data==
 
==Preliminary data==
 
===[[Peripheral T-cell lymphoma]]===
 
===[[Peripheral T-cell lymphoma]]===
# Shi Y, Dong M, Hong X, Zhang W, Feng J, Zhu J, Yu L, Ke X, Huang H, Shen Z, Fan Y, Li W, Zhao X, Qi J, Huang H, Zhou D, Ning Z, Lu X. Results from a multicenter, open-label, pivotal phase II study of chidamide in relapsed or refractory peripheral T-cell lymphoma. Ann Oncol. 2015 Aug;26(8):1766-71. Epub 2015 Jun 23. [http://annonc.oxfordjournals.org/content/26/8/1766.long link to original article] [http://www.ncbi.nlm.nih.gov/pubmed/26105599 PubMed]
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# Shi Y, Dong M, Hong X, Zhang W, Feng J, Zhu J, Yu L, Ke X, Huang H, Shen Z, Fan Y, Li W, Zhao X, Qi J, Huang H, Zhou D, Ning Z, Lu X. Results from a multicenter, open-label, pivotal phase II study of chidamide in relapsed or refractory peripheral T-cell lymphoma. Ann Oncol. 2015 Aug;26(8):1766-71. Epub 2015 Jun 23. [http://annonc.oxfordjournals.org/content/26/8/1766.long link to original article] [https://www.ncbi.nlm.nih.gov/pubmed/26105599 PubMed]
  
 
==History of changes in FDA indication==
 
==History of changes in FDA indication==

Revision as of 02:51, 2 December 2016

Mechanism of action

HDAC inhibitor

Preliminary data

Peripheral T-cell lymphoma

  1. Shi Y, Dong M, Hong X, Zhang W, Feng J, Zhu J, Yu L, Ke X, Huang H, Shen Z, Fan Y, Li W, Zhao X, Qi J, Huang H, Zhou D, Ning Z, Lu X. Results from a multicenter, open-label, pivotal phase II study of chidamide in relapsed or refractory peripheral T-cell lymphoma. Ann Oncol. 2015 Aug;26(8):1766-71. Epub 2015 Jun 23. link to original article PubMed

History of changes in FDA indication

Not FDA approved, but is approved for use in China.

Also known as

HBI-8000