Difference between revisions of "Steroid conversions"
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m (clarified equivalent dose to be for glucocorticoid effect) |
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{| class="wikitable sortable" border="1" style="text-align:center;" | {| class="wikitable sortable" border="1" style="text-align:center;" | ||
!Steroid | !Steroid | ||
| − | !Equivalent dose (mg) | + | !Equivalent (glucocorticoid) dose (mg) |
!Half-life (hours), biologic | !Half-life (hours), biologic | ||
!Relative anti-inflammatory (glucocorticoid) potency | !Relative anti-inflammatory (glucocorticoid) potency | ||
Revision as of 04:23, 15 March 2012
| Steroid | Equivalent (glucocorticoid) dose (mg) | Half-life (hours), biologic | Relative anti-inflammatory (glucocorticoid) potency | Relative mineralocorticoid (Na+ retaining) potency |
|---|---|---|---|---|
| Cortisone | 25 | 8-12 | 0.8 | 0.8 |
| Hydrocortisone | 20 | 8-12 | 1 | 1 |
| Prednisone | 5 | 18-36 | 4 | 0.8 |
| Prednisolone | 5 | 18-36 | 4 | 0.8 |
| Methylprednisolone (Solu-Medrol) | 4 | 18-36 | 5 | 0.5 |
| Dexamethasone (Decadron) | 0.75 | 36-54 | 25 | 0 |
References
- Meikle AW, Tyler FH. Potency and duration of action of glucocorticoids. Effects of hydrocortisone, prednisone and dexamethasone on human pituitary-adrenal function. Am J Med. 1977 Aug;63(2):200-7. PubMed