Difference between revisions of "User talk:Binunair2002"

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(info was added to regimen page)
 
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= LGL with treatment indications=
 
  
Regimen 1
 
== Methotrexate  +/- Prednisone==
 
*[[Methotrexate 7.5 to 10mg/m2 weekly po]] +
 
*[[Prednisone 1mg/kg po daily  x one month then taper over 1 months.]]
 
''' stop if no response by 4 months, if response continue until progression '''
 
 
Supportive medications:
 
 
===References===
 
 
# Bareau B, Rey J, Hamidou M, et al. Analysis of a French cohort of patients with large granular lymphocyte leukemia: a report on 229 cases. Haematologica 2010;95(9):1534-1541.[http://www.haematologica.org/content/95/9/1534.long#T3 long link to original article] [http://www.ncbi.nlm.nih.gov/pubmed?term=20378561 pubmed]
 
# Lamy T, Loughran TP.[http://www.ncbi.nlm.nih.gov/pubmed?term=21190991 ] How I treat LGL leukemia. Blood 2011; 117: 2764–2774.[http://www.ncbi.nlm.nih.gov/pubmed?term=21190991 link to original artcle ][http://www.ncbi.nlm.nih.gov/pubmed?term=21190991 pubmed]
 
 
Regimen 1
 
==Cyclophosphamide +/- Prednisone==
 
*[[ Cyclophosphamide 50-100 mg po daily
 
'''stop if no response by 4 months, if response continue for 6-12 months ,earlier if progression. Generous po fluid intake to prevent bladder toxicity'''
 
 
===References===
 
 
# Bareau B, Rey J, Hamidou M, et al. Analysis of a French cohort of patients with large granular lymphocyte leukemia: a report on 229 cases. Haematologica 2010;95(9):1534-1541.[http://www.haematologica.org/content/95/9/1534.long#T3 long link to original article] [http://www.ncbi.nlm.nih.gov/pubmed?term=20378561 pubmed]
 
# Lamy T, Loughran TP.[http://www.ncbi.nlm.nih.gov/pubmed?term=21190991 ] How I treat LGL leukemia. Blood 2011; 117: 2764–2774.[http://www.ncbi.nlm.nih.gov/pubmed?term=21190991 link to original article ][http://www.ncbi.nlm.nih.gov/pubmed?term=21190991 pubmed]
 
#Go RS, Li CY, Tefferi A, Phyliky RL(2001) Acquired pure red cell aplasia associated with lymphoproliferative disease of granular T lymphocytes. Blood 98:483–5 [http://bloodjournal.hematologylibrary.org/content/98/2/483.long link to original article ] [http://www.ncbi.nlm.nih.gov/pubmed?term=11435321  pubmed ]
 

Latest revision as of 02:15, 23 April 2014