Difference between revisions of "Steroid conversions"

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(Created page with "{| border="1" !Steroid !Equivalent dose (mg) !Half-life (hours), biologic !Relative anti-inflammatory (glucocorticoid) potency !Relative mineralocorticoid (Na+ retaining) potenc...")
 
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{| border="1"  
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{| border="1" align="center" style="text-align:center;"
 
!Steroid
 
!Steroid
 
!Equivalent dose (mg)
 
!Equivalent dose (mg)
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!Relative mineralocorticoid (Na+ retaining) potency
 
!Relative mineralocorticoid (Na+ retaining) potency
 
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|Cortisone
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|align="left" | Cortisone
 
|25
 
|25
 
|8-12
 
|8-12
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|0.8
 
|0.8
 
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|Hydrocortisone
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|align="left" | Hydrocortisone
 
|20
 
|20
 
|8-12
 
|8-12
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|1
 
|1
 
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|Prednisone
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|align="left" | Prednisone
 
|5
 
|5
 
|18-36
 
|18-36
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|0.8
 
|0.8
 
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|Prednisolone
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|align="left" | Prednisolone
 
|5
 
|5
 
|18-36
 
|18-36
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|0.8
 
|0.8
 
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|-
|Methylprednisolone (Solu-Medrol)
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|align="left" | Methylprednisolone (Solu-Medrol)
 
|4
 
|4
 
|18-36
 
|18-36
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|0.5
 
|0.5
 
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|Dexamethasone (Decadron)
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|align="left" | Dexamethasone (Decadron)
 
|0.75
 
|0.75
 
|36-54
 
|36-54

Revision as of 05:58, 3 December 2011

Steroid Equivalent dose (mg) Half-life (hours), biologic Relative anti-inflammatory (glucocorticoid) potency Relative mineralocorticoid (Na+ retaining) potency
Cortisone 25 8-12 0.8 0.8
Hydrocortisone 20 8-12 1 1
Prednisone 5 18-36 4 0.8
Prednisolone 5 18-36 4 0.8
Methylprednisolone (Solu-Medrol) 4 18-36 5 0.5
Dexamethasone (Decadron) 0.75 36-54 25 0

References

  1. Meikle AW, Tyler FH. Potency and duration of action of glucocorticoids. Effects of hydrocortisone, prednisone and dexamethasone on human pituitary-adrenal function. Am J Med. 1977 Aug;63(2):200-7. PubMed