Difference between revisions of "Degarelix (Firmagon)"
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==History of changes in FDA indication== | ==History of changes in FDA indication== | ||
| − | *12/24/2008: [http://www.fda.gov/AboutFDA/CentersOffices/OfficeofMedicalProductsandTobacco/CDER/ucm129207.htm FDA approved] | + | *12/24/2008: [http://www.fda.gov/AboutFDA/CentersOffices/OfficeofMedicalProductsandTobacco/CDER/ucm129207.htm FDA approved] for treatment of patients with advanced [[prostate cancer]]. |
==Also known as== | ==Also known as== | ||
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[[Category:Drugs]] | [[Category:Drugs]] | ||
[[Category:Subcutaneous medications]] | [[Category:Subcutaneous medications]] | ||
| − | + | ||
[[Category:GnRH antagonists]] | [[Category:GnRH antagonists]] | ||
[[Category:Prostate cancer medications]] | [[Category:Prostate cancer medications]] | ||
[[Category:FDA approved in 2008]] | [[Category:FDA approved in 2008]] | ||
Revision as of 22:30, 28 February 2020
General information
Class/mechanism: Gonadotropin-releasing hormone (GnRH) receptor antagonist. Reversibly binds to pituitary GnRH receptors, reducing the release of luteinizing hormone (LH) and follicle stimulation hormone (FSH), resulting in rapid androgen deprivation/decreased testosterone levels. There is no initial testosterone surge/flare with degarelix, in contrast to GnRH agonists.[1][2][3]
Route: SC
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
Patient drug information
History of changes in FDA indication
- 12/24/2008: FDA approved for treatment of patients with advanced prostate cancer.
Also known as
- Code name: ASP3550, FE200486
- Generic name: degarelix acetate
- Brand name: Firmagon