Difference between revisions of "Cytarabine (Ara-C)"
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*[http://www.uptodate.com/contents/cytarabine-patient-drug-information Cytarabine (Cytosar) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/cytarabine-patient-drug-information Cytarabine (Cytosar) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/cytarabine-patient-drug-information Cytarabine (Cytosar) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/cytarabine-patient-drug-information Cytarabine (Cytosar) patient drug information (UpToDate)]</ref> | ||
Revision as of 19:06, 5 December 2011
General information
Class/mechanism: Pyrimidine analog, mimics cytosine. Exact mechanism of action not known; believed to inhibit DNA polymerase, incorporate into DNA and RNA, and kill cells undergoing DNA synthesis (S-phase) and sometimes block cells from progressing from the G1 phase to the S-phase.[1][2]
Route: IV, IT, SC
Extravasation: no information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the package insert[1].
Patient drug information
- Cytarabine (Cytosar) patient drug information (Chemocare)[3]
- Cytarabine (Cytosar) patient drug information (UpToDate)[4]
Regimens
Standard format will be:
<acronym (if any)> <generic drug1, generic drug2, generic drug3, etc.> (disease)