Difference between revisions of "Carmustine (BCNU)"
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*[http://chemocare.com/chemotherapy/drug-info/carmustine.aspx Carmustine (BiCNU) patient drug information (Chemocare)]<ref>[http://chemocare.com/chemotherapy/drug-info/carmustine.aspx Carmustine (BiCNU) patient drug information (Chemocare)]</ref> | *[http://chemocare.com/chemotherapy/drug-info/carmustine.aspx Carmustine (BiCNU) patient drug information (Chemocare)]<ref>[http://chemocare.com/chemotherapy/drug-info/carmustine.aspx Carmustine (BiCNU) patient drug information (Chemocare)]</ref> | ||
*[http://www.uptodate.com/contents/carmustine-patient-drug-information Carmustine (BiCNU) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/carmustine-patient-drug-information Carmustine (BiCNU) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/carmustine-patient-drug-information Carmustine (BiCNU) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/carmustine-patient-drug-information Carmustine (BiCNU) patient drug information (UpToDate)]</ref> | ||
| + | |||
| + | ==History of changes in FDA indication== | ||
| + | *3/7/1977: Initial FDA approval | ||
| + | |||
| + | ==Also known as== | ||
| + | Precise Name: Carmustine (RXCUI 2105) | ||
| + | |||
| + | {| border="1" style="text-align:center;" | ||
| + | !colspan="8" align="center" style="background-color:#0066FF"| '''Synonyms''' | ||
| + | |- | ||
| + | |BCNU | ||
| + | |Becenun | ||
| + | |BiCNU | ||
| + | |Carmubris | ||
| + | |Carmustin Bcnu | ||
| + | |Gliadel | ||
| + | |Gliadel Wafer | ||
| + | |Leucerom | ||
| + | |- | ||
| + | |Nitrourean | ||
| + | |Nitrumon | ||
| + | |} | ||
==References== | ==References== | ||
Revision as of 02:14, 29 October 2013
Also known as bischloroethylnitrosourea, BCNU, or Carustine.
General information
Class/mechanism: Nitrosourea, alkylates DNA and RNA, inhibits several key enzymatic processes by carbamoylation of amino acids in proteins.[1][2]
Route: IV
Extravasation: vesicant/irritant
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
Patient drug information
- Carmustine (BiCNU) patient drug information (Chemocare)[3]
- Carmustine (BiCNU) patient drug information (UpToDate)[4]
History of changes in FDA indication
- 3/7/1977: Initial FDA approval
Also known as
Precise Name: Carmustine (RXCUI 2105)
| Synonyms | |||||||
|---|---|---|---|---|---|---|---|
| BCNU | Becenun | BiCNU | Carmubris | Carmustin Bcnu | Gliadel | Gliadel Wafer | Leucerom |
| Nitrourean | Nitrumon | ||||||