Difference between revisions of "Bortezomib (Velcade)"
(Created page with "==General information== Class/mechanism: Reversible inhibitor of the 26S proteasome, interfering with degradation of ubiquitinated proteins. This disrupts normal homeostatic mec...") |
|||
| Line 7: | Line 7: | ||
==Patient drug information== | ==Patient drug information== | ||
| + | *[http://chemocare.com/bio/bortezomib.asp Bortezomib (Velcade) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/bortezomib.asp Bortezomib (Velcade) patient drug information (Chemocare)]</ref> | ||
*[http://www.uptodate.com/contents/bortezomib-patient-drug-information Bortezomib (Velcade) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/bortezomib-patient-drug-information Bortezomib (Velcade) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/bortezomib-patient-drug-information Bortezomib (Velcade) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/bortezomib-patient-drug-information Bortezomib (Velcade) patient drug information (UpToDate)]</ref> | ||
Revision as of 18:47, 5 December 2011
General information
Class/mechanism: Reversible inhibitor of the 26S proteasome, interfering with degradation of ubiquitinated proteins. This disrupts normal homeostatic mechansims, leading to cell death.[1][2]
Route: IV, SC
Extravasation: irritant
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the package insert[1].
Patient drug information
- Bortezomib (Velcade) patient drug information (Chemocare)[3]
- Bortezomib (Velcade) patient drug information (UpToDate)[4]
Regimens
Standard format will be:
<acronym (if any)> <generic drug1, generic drug2, generic drug3, etc.> (disease)