Difference between revisions of "Zidovudine (Retrovir)"
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Warner-admin (talk | contribs) m (Text replacement - "[[Category:Drugs FDA" to "[[Category:FDA") |
Warner-admin (talk | contribs) m (Text replacement - "Category:Adult T-cell leukemia-lymphoma medications" to "Category:Adult T-cell leukemia/lymphoma medications") |
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Revision as of 17:13, 1 March 2019
Mechanism of action
From the NCI Drug Dictionary: A synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyrimidines.
Diseases for which it is used
Also known as
- Generic names: azidothymidine, AZT, ZDV
- Brand names: Aztec, Retrovir