Difference between revisions of "Dalteparin (Fragmin)"
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==Also known as== | ==Also known as== | ||
| − | + | *'''Brand names:''' Daltepan, Daltepin, Fluzepamin, Fragmin, Fragmine, Fragminject, Fresubaru, Hepachron, Hepagumin, Ligofragmin, Low Liquemin, Resolmin | |
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==References== | ==References== | ||
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[[Category:Drug index]] | [[Category:Drug index]] | ||
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[[Category:Subcutaneous medications]] | [[Category:Subcutaneous medications]] | ||
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[[Category:Heparins]] | [[Category:Heparins]] | ||
[[Category:Low molecular weight heparins]] | [[Category:Low molecular weight heparins]] | ||
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| + | [[Category:Venous thromboembolism (VTE) medications]] | ||
[[Category:Drugs FDA approved in 1994]] | [[Category:Drugs FDA approved in 1994]] | ||
Revision as of 02:26, 8 June 2018
General information
Class/mechanism: Low molecular weight heparin, binds to antithrombin III, accelerating its activity and inhibiting factor Xa and thrombin.[1][2][3]
Route: SC
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Patient drug information
- Brief patient counseling information can be found in the Dalteparin (Fragmin) package insert[1]
- Dalteparin (Fragmin) patient drug information (UpToDate)[4]
History of changes in FDA indication
- 12/22/1994: Initial FDA approval "for the prophylaxis of deep vein thrombosis (DVT), which may lead to pulmonary embolism (PE) in patients undergoing hip replacement surgery."
- Subsequently FDA approved for "Prophylaxis of deep vein thrombosis (DVT) in abdominal surgery, hip replacement surgery or medical patients with severely restricted mobility during acute illness" and "Extended treatment of symptomatic venous thromboembolism (VTE) to reduce the recurrence in patients with cancer. In these patients, the FRAGMIN therapy begins with the initial VTE treatment and continues for six months."
Also known as
- Brand names: Daltepan, Daltepin, Fluzepamin, Fragmin, Fragmine, Fragminject, Fresubaru, Hepachron, Hepagumin, Ligofragmin, Low Liquemin, Resolmin