Von Willebrand factor and factor VIII complex, human

Also known as Alphanate, antihemophilic factor/von Willebrand Factor complex, Humate-P, Wilate, or Wilfactin.

General information

Class/mechanism: Von Willebrand Factor (vWF) and coagulation factor VIII complex; allows for improved platelet function & coagulation in patients with von Willebrand Disease (vWD) and/or hemophilia A. VWF mediates binding between platelets and damaged endothelial tissue in addition to functioning as a carrier protein for factor VIII, which is a participant in the coagulation cascade.
Please choose from the products below to find specific drug/manufacturer information:

• Alphanate (human)
• Humate-P (human)
• Wilate (human)

Route: IV
Extravasation: no information

For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.

Patient drug information

• Von Willebrand Factor and factor VIII complex, human patient drug information (UpToDate)