Difference between revisions of "Mepolizumab (Nucala)"

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=General information=
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==General information==
 
Class/mechanism: A humanized monoclonal antibody targeting interleukin-5 (IL-5).  
 
Class/mechanism: A humanized monoclonal antibody targeting interleukin-5 (IL-5).  
  
=Preliminary data=
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==Diseases for which it is used==
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*[[Hypereosinophilic syndrome (HES)]]
  
==[[Hypereosinophilic syndrome (HES)]]==
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==History of changes in FDA indication==
# Rothenberg ME, Klion AD, Roufosse FE, Kahn JE, Weller PF, Simon HU, Schwartz LB, Rosenwasser LJ, Ring J, Griffin EF, Haig AE, Frewer PI, Parkin JM, Gleich GJ; Mepolizumab HES Study Group. Treatment of patients with the hypereosinophilic syndrome with mepolizumab. N Engl J Med. 2008 Mar 20;358(12):1215-28. Epub 2008 Mar 16. Erratum in: N Engl J Med. 2008 Jun 5;358(23): 2530. [http://www.nejm.org/doi/full/10.1056/NEJMoa070812 link to original article] [http://www.ncbi.nlm.nih.gov/pubmed/18344568 PubMed]
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''No approval for hematology/oncology conditions, at this time.''
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==Also known as==
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*'''Brand names:''' Bosatria, Nucala
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[[Category:Drugs]]
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[[Category:Intravenous medications]]
  
[[Category:Drug index]]
 
[[Category:Immunotherapy]]
 
  
[[Category:Antibody medications]]
 
 
[[Category:Anti-IL-5 antibodies]]
 
[[Category:Anti-IL-5 antibodies]]
  
[[Category:Investigational]]
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[[Category:Hypereosinophilic syndrome medications]]
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[[Category:FDA approved in 2015]]

Latest revision as of 19:47, 27 February 2020

General information

Class/mechanism: A humanized monoclonal antibody targeting interleukin-5 (IL-5).

Diseases for which it is used

History of changes in FDA indication

No approval for hematology/oncology conditions, at this time.

Also known as

  • Brand names: Bosatria, Nucala