Difference between revisions of "Agatolimod (PF-3512676)"
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==Mechanism of action== | ==Mechanism of action== | ||
| − | From the NCI Drug Dictionary: The tricosasodium salt of a synthetic 24-mer oligonucleotide containing 3 CpG motifs with potential antineoplastic and immunostimulatory activity. Agatolimod selectively targets Toll-like receptor 9 (TLR9), thereby activating dendritic and B cells and stimulating cytotoxic T cell and antibody responses against tumor cells bearing tumor antigens. | + | From the [https://www.cancer.gov/publications/dictionaries/cancer-drug/def/agatolimod-sodium NCI Drug Dictionary]: The tricosasodium salt of a synthetic 24-mer oligonucleotide containing 3 CpG motifs with potential antineoplastic and immunostimulatory activity. Agatolimod selectively targets Toll-like receptor 9 (TLR9), thereby activating dendritic and B cells and stimulating cytotoxic T cell and antibody responses against tumor cells bearing tumor antigens. |
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| + | ==Also known as== | ||
| + | *'''Code name:''' PF-3512676 | ||
[[Category:Drugs]] | [[Category:Drugs]] | ||
| − | [[Category: | + | [[Category:Intravenous medications]] |
| + | [[Category:TLR9 agonists]] | ||
[[Category:Investigational drugs]] | [[Category:Investigational drugs]] | ||
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Latest revision as of 02:29, 26 July 2023
Mechanism of action
From the NCI Drug Dictionary: The tricosasodium salt of a synthetic 24-mer oligonucleotide containing 3 CpG motifs with potential antineoplastic and immunostimulatory activity. Agatolimod selectively targets Toll-like receptor 9 (TLR9), thereby activating dendritic and B cells and stimulating cytotoxic T cell and antibody responses against tumor cells bearing tumor antigens.
Also known as
- Code name: PF-3512676