Difference between revisions of "Sapacitabine (CS-682)"

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==Mechanism of action==
 
==Mechanism of action==
Pyrimidine analogue
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Pyrimidine analog
  
 
==Preliminary results==
 
==Preliminary results==
 
===[[Acute myeloid leukemia]]===
 
===[[Acute myeloid leukemia]]===
# Hagop Kantarjian, Stefan Faderl, Guillermo Garcia-Manero, Selina Luger, Parameswaran Venugopal, Lori Maness, Meir Wetzler, Steven Coutre, Wendy Stock, David Claxton, Stuart L Goldberg, Martha Arellano, Stephen A Strickland, Karen Seiter, Gary Schiller, Elias Jabbour, Judy Chiao, William Plunkett, Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study, The Lancet Oncology, Volume 13, Issue 11, November 2012, Pages 1096-1104, ISSN 1470-2045, 10.1016/S1470-2045(12)70436-9. [http://www.sciencedirect.com/science/article/pii/S1470204512704369 link to article]
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# '''CYC682-06:''' Kantarjian H, Faderl S, Garcia-Manero G, Luger S, Venugopal P, Maness L, Wetzler M, Coutre S, Stock W, Claxton D, Goldberg SL, Arellano M, Strickland SA, Seiter K, Schiller G, Jabbour E, Chiao J, Plunkett W. Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study. Lancet Oncol. 2012 Nov;13(11):1096-104. Epub 2012 Oct 15. [https://doi.org/10.1016/S1470-2045(12)70436-9 link to original article] [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004358/ link to PMC article] [https://pubmed.ncbi.nlm.nih.gov/23075701/ PubMed] [https://clinicaltrials.gov/study/NCT00590187 NCT00590187]
  
[Category:Drug index]]
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==Also known as==
[[Category:Chemotherapy]]
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*'''Code name:''' CS-682
[[Category:Oral chemotherapy]]
 
  
[[Category:Pyrimidine analogues]]
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[[Category:Drugs]]
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[[Category:Oral medications]]
  
[[Category:Acute myeloid leukemia medications]]
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[[Category:Pyrimidine analogs]]
  
[[Category:Investigational]]
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[[Category:Acute myeloid leukemia medications (investigational)]]
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[[Category:Investigational drugs]]

Latest revision as of 13:51, 23 September 2023

Mechanism of action

Pyrimidine analog

Preliminary results

Acute myeloid leukemia

  1. CYC682-06: Kantarjian H, Faderl S, Garcia-Manero G, Luger S, Venugopal P, Maness L, Wetzler M, Coutre S, Stock W, Claxton D, Goldberg SL, Arellano M, Strickland SA, Seiter K, Schiller G, Jabbour E, Chiao J, Plunkett W. Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study. Lancet Oncol. 2012 Nov;13(11):1096-104. Epub 2012 Oct 15. link to original article link to PMC article PubMed NCT00590187

Also known as

  • Code name: CS-682