Difference between revisions of "Sapacitabine (CS-682)"
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==Mechanism of action== | ==Mechanism of action== | ||
| − | Pyrimidine | + | Pyrimidine analog |
==Preliminary results== | ==Preliminary results== | ||
===[[Acute myeloid leukemia]]=== | ===[[Acute myeloid leukemia]]=== | ||
| − | # '''CYC682-06:''' Kantarjian H, Faderl S, Garcia-Manero G, Luger S, Venugopal P, Maness L, Wetzler M, Coutre S, Stock W, Claxton D, Goldberg SL, Arellano M, Strickland SA, Seiter K, Schiller G, Jabbour E, Chiao J, Plunkett W. Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study. Lancet Oncol. 2012 Nov;13(11):1096-104. Epub 2012 Oct 15. [https:// | + | # '''CYC682-06:''' Kantarjian H, Faderl S, Garcia-Manero G, Luger S, Venugopal P, Maness L, Wetzler M, Coutre S, Stock W, Claxton D, Goldberg SL, Arellano M, Strickland SA, Seiter K, Schiller G, Jabbour E, Chiao J, Plunkett W. Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study. Lancet Oncol. 2012 Nov;13(11):1096-104. Epub 2012 Oct 15. [https://doi.org/10.1016/S1470-2045(12)70436-9 link to original article] [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004358/ link to PMC article] [https://pubmed.ncbi.nlm.nih.gov/23075701/ PubMed] [https://clinicaltrials.gov/study/NCT00590187 NCT00590187] |
==Also known as== | ==Also known as== | ||
| Line 12: | Line 12: | ||
[[Category:Oral medications]] | [[Category:Oral medications]] | ||
| − | [[Category:Pyrimidine | + | [[Category:Pyrimidine analogs]] |
[[Category:Acute myeloid leukemia medications (investigational)]] | [[Category:Acute myeloid leukemia medications (investigational)]] | ||
[[Category:Investigational drugs]] | [[Category:Investigational drugs]] | ||
Latest revision as of 13:51, 23 September 2023
Mechanism of action
Pyrimidine analog
Preliminary results
Acute myeloid leukemia
- CYC682-06: Kantarjian H, Faderl S, Garcia-Manero G, Luger S, Venugopal P, Maness L, Wetzler M, Coutre S, Stock W, Claxton D, Goldberg SL, Arellano M, Strickland SA, Seiter K, Schiller G, Jabbour E, Chiao J, Plunkett W. Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study. Lancet Oncol. 2012 Nov;13(11):1096-104. Epub 2012 Oct 15. link to original article link to PMC article PubMed NCT00590187
Also known as
- Code name: CS-682