Difference between revisions of "Opioid Conversion Table"

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''Note: There are disagreements about the accuracy of these conversions, which were mostly established in healthy persons. If and when guidelines on this topic are available regarding cancer-related pain, we will add them here.''
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=Morphine milligram equivalent (MME)=
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*Oral morphine: 1 MME
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*Hydrocodone: 1 MME
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*Oxycodone: 1.5 MME
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*IV morphine: 3 MME
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*Oral hydromorphone: 4 MME
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*IV hydromorphone: 20 MME
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=Conversion table using common doses=
 
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===Morphine : Methadone have a dose based adjustment===
 
===Morphine : Methadone have a dose based adjustment===
Up to 100mg/day Morphine --> 4:1 of Methadone
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Up to 100 mg/day Morphine --> 4:1 of Methadone
  
101-300mg/day Morphine --> 8:1 of Methadone  
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101-300 mg/day Morphine --> 8:1 of Methadone  
  
301-500mg/day Morphine --> 12:1 of Methadone  
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301-500 mg/day Morphine --> 12:1 of Methadone  
  
501-1000mg/day Morphine --> 15:1 of Methadone
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501-1000 mg/day Morphine --> 15:1 of Methadone
  
 
>1001mg/day Morphine --> 20:1 of Methadone
 
>1001mg/day Morphine --> 20:1 of Methadone
  
 
[[Category:General reference pages]]
 
[[Category:General reference pages]]
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[[Category:Clinical pharmacology]]

Latest revision as of 16:37, 19 April 2024

Note: There are disagreements about the accuracy of these conversions, which were mostly established in healthy persons. If and when guidelines on this topic are available regarding cancer-related pain, we will add them here.

Morphine milligram equivalent (MME)

  • Oral morphine: 1 MME
  • Hydrocodone: 1 MME
  • Oxycodone: 1.5 MME
  • IV morphine: 3 MME
  • Oral hydromorphone: 4 MME
  • IV hydromorphone: 20 MME

Conversion table using common doses

Opioid IV/SubQ/IM (mg) PO/Rectal (mg)
Morphine 10 30
Hydrocodone - 30
Oxycodone - 20
Hydromorphone 1.5 7.5
Codeine - 200
Hydrocodone - 30
Tramadol - 100
Fentanyl* 0.1 -

*Fentanyl dosing is only for intermittent bolus dosing.

To convert Fentanyl boluses to Fentanyl patch, please see example opioid conversions.

Morphine : Methadone have a dose based adjustment

Up to 100 mg/day Morphine --> 4:1 of Methadone

101-300 mg/day Morphine --> 8:1 of Methadone

301-500 mg/day Morphine --> 12:1 of Methadone

501-1000 mg/day Morphine --> 15:1 of Methadone

>1001mg/day Morphine --> 20:1 of Methadone