Difference between revisions of "Opioid Conversion Table"
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(Created page with "{| class="wikitable" |- ! Opioid !! IV/SubQ/IM (mg) !! PO/Rectal (mg) |- | Morphine || 10 || 30 |- | Hydrocodone ||- || 30 |- | Oxycodone ||- || 20 |- | Hydromorphone || 1....") |
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| + | ''Note: There are disagreements about the accuracy of these conversions, which were mostly established in healthy persons. If and when guidelines on this topic are available regarding cancer-related pain, we will add them here.'' | ||
| + | =Morphine milligram equivalent (MME)= | ||
| + | *Oral morphine: 1 MME | ||
| + | *Hydrocodone: 1 MME | ||
| + | *Oxycodone: 1.5 MME | ||
| + | *IV morphine: 3 MME | ||
| + | *Oral hydromorphone: 4 MME | ||
| + | *IV hydromorphone: 20 MME | ||
| + | |||
| + | =Conversion table using common doses= | ||
{| class="wikitable" | {| class="wikitable" | ||
|- | |- | ||
| − | ! Opioid !! IV/SubQ/IM (mg) !! PO/Rectal (mg) | + | !Opioid!!IV/SubQ/IM (mg)!!PO/Rectal (mg) |
|- | |- | ||
| − | | Morphine || 10 || 30 | + | |Morphine||10||30 |
|- | |- | ||
| − | | Hydrocodone ||- || 30 | + | |Hydrocodone||-||30 |
|- | |- | ||
| − | | Oxycodone ||- || 20 | + | |Oxycodone||-||20 |
|- | |- | ||
| − | | Hydromorphone || 1.5 || 7.5 | + | |Hydromorphone||1.5||7.5 |
|- | |- | ||
| + | |Codeine | ||
| + | | - | ||
| + | |200 | ||
| + | |- | ||
| + | |Hydrocodone | ||
| + | | - | ||
| + | |30 | ||
| + | |- | ||
| + | |Tramadol | ||
| + | | - | ||
| + | |100 | ||
| + | |- | ||
| + | |Fentanyl* | ||
| + | |0.1 | ||
| + | | - | ||
| + | |- | ||
| + | |} | ||
| + | <nowiki>*</nowiki>Fentanyl dosing is only for intermittent bolus dosing. | ||
| + | |||
| + | To convert Fentanyl boluses to Fentanyl patch, please see example opioid conversions. | ||
| + | |||
| + | ===Morphine : Methadone have a dose based adjustment=== | ||
| + | Up to 100 mg/day Morphine --> 4:1 of Methadone | ||
| + | |||
| + | 101-300 mg/day Morphine --> 8:1 of Methadone | ||
| + | |||
| + | 301-500 mg/day Morphine --> 12:1 of Methadone | ||
| + | |||
| + | 501-1000 mg/day Morphine --> 15:1 of Methadone | ||
| + | |||
| + | >1001mg/day Morphine --> 20:1 of Methadone | ||
| + | |||
| + | [[Category:General reference pages]] | ||
| + | [[Category:Clinical pharmacology]] | ||
Latest revision as of 16:37, 19 April 2024
Note: There are disagreements about the accuracy of these conversions, which were mostly established in healthy persons. If and when guidelines on this topic are available regarding cancer-related pain, we will add them here.
Morphine milligram equivalent (MME)
- Oral morphine: 1 MME
- Hydrocodone: 1 MME
- Oxycodone: 1.5 MME
- IV morphine: 3 MME
- Oral hydromorphone: 4 MME
- IV hydromorphone: 20 MME
Conversion table using common doses
| Opioid | IV/SubQ/IM (mg) | PO/Rectal (mg) |
|---|---|---|
| Morphine | 10 | 30 |
| Hydrocodone | - | 30 |
| Oxycodone | - | 20 |
| Hydromorphone | 1.5 | 7.5 |
| Codeine | - | 200 |
| Hydrocodone | - | 30 |
| Tramadol | - | 100 |
| Fentanyl* | 0.1 | - |
*Fentanyl dosing is only for intermittent bolus dosing.
To convert Fentanyl boluses to Fentanyl patch, please see example opioid conversions.
Morphine : Methadone have a dose based adjustment
Up to 100 mg/day Morphine --> 4:1 of Methadone
101-300 mg/day Morphine --> 8:1 of Methadone
301-500 mg/day Morphine --> 12:1 of Methadone
501-1000 mg/day Morphine --> 15:1 of Methadone
>1001mg/day Morphine --> 20:1 of Methadone