Difference between revisions of "Sapacitabine (CS-682)"

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(Created page with "=Preliminary results= ==Phase II== # Hagop Kantarjian, Stefan Faderl, Guillermo Garcia-Manero, Selina Luger, Parameswaran Venugopal, Lori Maness, Meir Wetzler, Steven Coutre,...")
 
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=Preliminary results=
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==Mechanism of action==
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Pyrimidine analog
  
==Phase II==
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==Preliminary results==
# Hagop Kantarjian, Stefan Faderl, Guillermo Garcia-Manero, Selina Luger, Parameswaran Venugopal, Lori Maness, Meir Wetzler, Steven Coutre, Wendy Stock, David Claxton, Stuart L Goldberg, Martha Arellano, Stephen A Strickland, Karen Seiter, Gary Schiller, Elias Jabbour, Judy Chiao, William Plunkett, Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study, The Lancet Oncology, Volume 13, Issue 11, November 2012, Pages 1096-1104, ISSN 1470-2045, 10.1016/S1470-2045(12)70436-9. [http://www.sciencedirect.com/science/article/pii/S1470204512704369 link to article]
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===[[Acute myeloid leukemia]]===
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# '''CYC682-06:''' Kantarjian H, Faderl S, Garcia-Manero G, Luger S, Venugopal P, Maness L, Wetzler M, Coutre S, Stock W, Claxton D, Goldberg SL, Arellano M, Strickland SA, Seiter K, Schiller G, Jabbour E, Chiao J, Plunkett W. Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study. Lancet Oncol. 2012 Nov;13(11):1096-104. Epub 2012 Oct 15. [https://doi.org/10.1016/S1470-2045(12)70436-9 link to original article] [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004358/ link to PMC article] [https://pubmed.ncbi.nlm.nih.gov/23075701/ PubMed] [https://clinicaltrials.gov/study/NCT00590187 NCT00590187]
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==Also known as==
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*'''Code name:''' CS-682
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[[Category:Drugs]]
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[[Category:Oral medications]]
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[[Category:Pyrimidine analogs]]
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[[Category:Acute myeloid leukemia medications (investigational)]]
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[[Category:Investigational drugs]]

Latest revision as of 13:51, 23 September 2023

Mechanism of action

Pyrimidine analog

Preliminary results

Acute myeloid leukemia

  1. CYC682-06: Kantarjian H, Faderl S, Garcia-Manero G, Luger S, Venugopal P, Maness L, Wetzler M, Coutre S, Stock W, Claxton D, Goldberg SL, Arellano M, Strickland SA, Seiter K, Schiller G, Jabbour E, Chiao J, Plunkett W. Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study. Lancet Oncol. 2012 Nov;13(11):1096-104. Epub 2012 Oct 15. link to original article link to PMC article PubMed NCT00590187

Also known as

  • Code name: CS-682