Difference between revisions of "Eosinophilia"
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==Definition== | ==Definition== | ||
| − | *Mild eosinophilia: Absolute eosinophil count 500 to 1500 cells/ | + | *Mild eosinophilia: Absolute eosinophil count 500 to 1500 cells/μL |
| − | *Moderate eosinophilia: Absolute eosinophil count 1500 to 5000 cells/ | + | *Moderate eosinophilia: Absolute eosinophil count 1500 to 5000 cells/μL |
| − | *Severe eosinophilia: Absolute eosinophil count >5000 cells/ | + | *Severe eosinophilia: Absolute eosinophil count >5000 cells/μL |
==Evaluation== | ==Evaluation== | ||
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*CHIC2, 4q12 Deletion (FIP1L1 and PDGFRA Fusion) FISH. | *CHIC2, 4q12 Deletion (FIP1L1 and PDGFRA Fusion) FISH. | ||
*T-Cell Receptor Gene Rearrangement PCR. | *T-Cell Receptor Gene Rearrangement PCR. | ||
| + | *Flow cytometry | ||
*BCR-ABL FISH | *BCR-ABL FISH | ||
*Immunoglobulins IgG, IgA, IgM | *Immunoglobulins IgG, IgA, IgM | ||
Latest revision as of 12:16, 18 August 2023
Definition
- Mild eosinophilia: Absolute eosinophil count 500 to 1500 cells/μL
- Moderate eosinophilia: Absolute eosinophil count 1500 to 5000 cells/μL
- Severe eosinophilia: Absolute eosinophil count >5000 cells/μL
Evaluation
May consist of:
- CBC with differential
- Comprehensive metabolic panel (CMP)
- Peripheral smear
- Vitamin B12
- Troponin I
- CK
- ANCA
- Strongyloides Antibody
- CHIC2, 4q12 Deletion (FIP1L1 and PDGFRA Fusion) FISH.
- T-Cell Receptor Gene Rearrangement PCR.
- Flow cytometry
- BCR-ABL FISH
- Immunoglobulins IgG, IgA, IgM
- Cortisol
- HIV, HTLV-I, HTLV-II serologies
- Serum tryptase
- Stool ova and parasites
- Chest x-ray
- Echocardiogram
- CT scans to evaluate for pulmonary pathology, lymphadenopathy
- Bone marrow biopsy
- Pulmonary function tests (PFTs)
- Clinical/infection history, international travel
- Medications