Difference between revisions of "Mitomycin (Mutamycin)"
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(Created page with "==General information== Class/mechanism: <ref name="insert">[http://patient.cancerconsultants.com/druginserts/Mitomycin.pdf Mitomycin (Mutamycin) package insert]</ref><ref>[http:...") |
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| + | Also known as Mitomycin-C or MTC. | ||
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==General information== | ==General information== | ||
| − | Class/mechanism: <ref name="insert">[http://patient.cancerconsultants.com/druginserts/Mitomycin.pdf Mitomycin (Mutamycin) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/mitomycin.pdf Mitomycin (Mutamycin) package insert (locally hosted backup)]</ref> | + | Class/mechanism: Antibiotic oncologic isolated from Streptomyces caespitosus; inhibits DNA synthesis and induces crosslinking. At higher concentrations, can also inhibit RNA and protein synthesis.<ref name="insert">[http://patient.cancerconsultants.com/druginserts/Mitomycin.pdf Mitomycin (Mutamycin) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/mitomycin.pdf Mitomycin (Mutamycin) package insert (locally hosted backup)]</ref> |
| − | <br>Route: | + | <br>Route: IV |
| − | <br>Extravasation: | + | <br>Extravasation: [[vesicant]] |
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the package insert<ref name="insert"></ref>. | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the package insert<ref name="insert"></ref>. | ||
Revision as of 20:19, 23 February 2012
Also known as Mitomycin-C or MTC.
General information
Class/mechanism: Antibiotic oncologic isolated from Streptomyces caespitosus; inhibits DNA synthesis and induces crosslinking. At higher concentrations, can also inhibit RNA and protein synthesis.[1][2]
Route: IV
Extravasation: vesicant
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the package insert[1].
Patient drug information
- Mitomycin (Mutamycin) patient drug information (Chemocare)[3]
- Mitomycin (Mutamycin) patient drug information (UpToDate)[4]