Difference between revisions of "Mechlorethamine (Mustargen)"
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==General information== | ==General information== | ||
| − | Class/mechanism: <ref name="insert">[http://patient.cancerconsultants.com/druginserts/Mechlorethamine.pdf Mechlorethamine (Mustargen) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/mechlorethamine.pdf Mechlorethamine (Mustargen) package insert (locally hosted backup)]</ref> | + | Class/mechanism: Nitrogen mustard, alkylator. Crosslinks DNA, interfering with cell replication.<ref name="insert">[http://patient.cancerconsultants.com/druginserts/Mechlorethamine.pdf Mechlorethamine (Mustargen) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/mechlorethamine.pdf Mechlorethamine (Mustargen) package insert (locally hosted backup)]</ref> |
| − | <br>Route: | + | <br>Route: IV, intracavitary |
| − | <br>Extravasation: | + | <br>Extravasation: [[vesicant]] |
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the package insert<ref name="insert"></ref>. | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the package insert<ref name="insert"></ref>. | ||
==Patient drug information== | ==Patient drug information== | ||
| − | *[http://chemocare.com/bio/mechlorethamine.asp Mechlorethamine (Mustargen) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/mechlorethamine. | + | *[http://chemocare.com/bio/mechlorethamine.asp Mechlorethamine (Mustargen) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/mechlorethamine.asp Mechlorethamine (Mustargen) patient drug information (Chemocare)]</ref> |
*[http://www.uptodate.com/contents/mechlorethamine-patient-drug-information Mechlorethamine (Mustargen) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/mechlorethamine-patient-drug-information Mechlorethamine (Mustargen) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/mechlorethamine-patient-drug-information Mechlorethamine (Mustargen) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/mechlorethamine-patient-drug-information Mechlorethamine (Mustargen) patient drug information (UpToDate)]</ref> | ||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 19:31, 23 February 2012
General information
Class/mechanism: Nitrogen mustard, alkylator. Crosslinks DNA, interfering with cell replication.[1][2]
Route: IV, intracavitary
Extravasation: vesicant
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the package insert[1].
Patient drug information
- Mechlorethamine (Mustargen) patient drug information (Chemocare)[3]
- Mechlorethamine (Mustargen) patient drug information (UpToDate)[4]