Difference between revisions of "Paclitaxel, nanoparticle albumin-bound (Abraxane)"
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==General information== | ==General information== | ||
| − | Class/mechanism: Taxane, promotes assembly of microtubules, stablizes microtubules, preventing depolymerization, inhibiting interphase/mitosis processes<ref name="insert">[http://www.abraxane.com/docs/Abraxane_PrescribingInformation.pdf Paclitaxel, albumin-bound (Abraxane) package insert]</ref><ref>[http://hemonc.org/docs/chemotherapypackageinsert/aldesleukin.pdf Paclitaxel, albumin-bound (Abraxane) package insert (locally hosted backup)]</ref> | + | Class/mechanism: Taxane, promotes assembly of microtubules, stablizes microtubules, preventing depolymerization, inhibiting interphase/mitosis processes.<ref name="insert">[http://www.abraxane.com/docs/Abraxane_PrescribingInformation.pdf Paclitaxel, albumin-bound (Abraxane) package insert]</ref><ref>[http://hemonc.org/docs/chemotherapypackageinsert/aldesleukin.pdf Paclitaxel, albumin-bound (Abraxane) package insert (locally hosted backup)]</ref> |
<br>Route: IV | <br>Route: IV | ||
<br>Extravasation: [[irritant]] | <br>Extravasation: [[irritant]] | ||
Revision as of 17:07, 22 February 2012
Also known as nab-paclitaxel.
General information
Class/mechanism: Taxane, promotes assembly of microtubules, stablizes microtubules, preventing depolymerization, inhibiting interphase/mitosis processes.[1][2]
Route: IV
Extravasation: irritant
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the package insert[1].