Difference between revisions of "Vindesine (Eldisine)"
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==Diseases for which it is used== | ==Diseases for which it is used== | ||
*[[Burkitt lymphoma]] | *[[Burkitt lymphoma]] | ||
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*[[Diffuse large B-cell lymphoma]] | *[[Diffuse large B-cell lymphoma]] | ||
*[[HIV-associated lymphoma]] | *[[HIV-associated lymphoma]] | ||
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[[Category:Burkitt lymphoma medications]] | [[Category:Burkitt lymphoma medications]] | ||
| + | [[Category:Central nervous system (CNS) lymphoma medications]] | ||
[[Category:Diffuse large B-cell lymphoma medications]] | [[Category:Diffuse large B-cell lymphoma medications]] | ||
[[Category:HIV-associated lymphoma medications]] | [[Category:HIV-associated lymphoma medications]] | ||
[[Category:Non-small cell lung cancer medications]] | [[Category:Non-small cell lung cancer medications]] | ||
Revision as of 15:35, 5 June 2015
General information
Class/mechanism: Vinca alkaloid, inhibits microtubule formation in the mitotic spindle, causing cell cycle arrest in metaphase.[1][2]
Route: IV
Extravasation: vesicant
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
- Burkitt lymphoma
- CNS lymphoma
- Diffuse large B-cell lymphoma
- HIV-associated lymphoma
- Non-small cell lung cancer
Patient drug information
- Vindesine (Eldisine) patient information at Macmillan Cancer Support[3]
- Vindesine (Eldisine) patient information at Genus Pharmaceuticals[4]
- Vindesine (Eldisine) patient drug information (UpToDate)[5]
History of changes in FDA indication
Not approved by the FDA. Approved for use in some countries e.g. Britain, South Africa.
Also known as
Desacetylvinblastine amide, DAVA, DVA, Eldesine, Fildesin, or VDS.
References
- ↑ 1.0 1.1 Vindesine (Eldisine) package insert
- ↑ Vindesine (Eldisine) package insert (locally hosted backup)
- ↑ Vindesine (Eldisine) patient information at Macmillan Cancer Support
- ↑ Vindesine (Eldisine) patient information at Genus Pharmaceuticals
- ↑ Vindesine (Eldisine) patient drug information (UpToDate)