Difference between revisions of "Cytarabine and daunorubicin liposomal (Vyxeos)"
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[[Category:Anthracyclines]] | [[Category:Anthracyclines]] | ||
[[Category:Antimetabolites]] | [[Category:Antimetabolites]] | ||
− | [[Category:Deoxycytidine | + | [[Category:Deoxycytidine analogs]] |
− | [[Category:Topoisomerase inhibitors]] | + | [[Category:Topoisomerase II inhibitors]] |
[[Category:Acute myeloid leukemia medications]] | [[Category:Acute myeloid leukemia medications]] |
Latest revision as of 13:34, 23 September 2023
Mechanism of action
This drug is a liposomal formulation of Cytarabine (Ara-C) and Daunorubicin (Cerubidine) in a 5:1 molar ratio. [1][2][3]
Route: IV
Extravasation: no information
Disease for which it is established
History of changes in FDA indication
- 2017-08-03: Granted FDA regular approval for the treatment of adults with newly-diagnosed therapy-related AML (t-AML) or AML with myelodysplasia-related changes (AML-MRC), two types of AML having a poor prognosis. (Based on CLTR0310-301)
History of changes in EMA indication
- 2018-08-23: Initial authorization
Patient Information
Also known as
- Code name: CPX-351
- Brand name: Vyxeos, Vyxeos liposomal