Difference between revisions of "Lestaurtinib (CEP-701)"
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| − | + | ==Mechanism of action== | |
| + | From the [https://www.cancer.gov/publications/dictionaries/cancer-drug/def/lestaurtinib NCI Drug Dictionary]: An orally bioavailable indolocarbazole derivative with antineoplastic properties. Lestaurtinib inhibits autophosphorylation of FMS-like tyrosine kinase 3 (FLT3), resulting in inhibition of FLT3 activity and induction of apoptosis in tumor cells that overexpress FLT3. | ||
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| + | ==Also known as== | ||
| + | *'''Code name:''' CEP-701 | ||
[[Category:Drugs]] | [[Category:Drugs]] | ||
| − | [[Category: | + | [[Category:Oral medications]] |
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[[Category:FLT3 inhibitors]] | [[Category:FLT3 inhibitors]] | ||
| − | [[Category: | + | [[Category:JAK2 inhibitors]] |
[[Category:Investigational drugs]] | [[Category:Investigational drugs]] | ||
| + | [[Category:Stub]] | ||
Latest revision as of 11:24, 23 September 2023
Mechanism of action
From the NCI Drug Dictionary: An orally bioavailable indolocarbazole derivative with antineoplastic properties. Lestaurtinib inhibits autophosphorylation of FMS-like tyrosine kinase 3 (FLT3), resulting in inhibition of FLT3 activity and induction of apoptosis in tumor cells that overexpress FLT3.
Also known as
- Code name: CEP-701