Difference between revisions of "GD2-CART01"
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(Created page with "==Mechanism of action== CAR-T ==Preliminary data== ===Neuroblastoma=== #'''GD2CAR01:''' Del Bufalo F, De Angelis B, Caruana I, Del Baldo G, De Ioris MA, Serra A, Mastronu...") |
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==Mechanism of action== | ==Mechanism of action== | ||
| − | CAR- | + | Anti-GD2 CAR T-cell |
==Preliminary data== | ==Preliminary data== | ||
===[[Neuroblastoma]]=== | ===[[Neuroblastoma]]=== | ||
| − | #'''GD2CAR01:''' Del Bufalo F, De Angelis B, Caruana I, Del Baldo G, De Ioris MA, Serra A, Mastronuzzi A, Cefalo MG, Pagliara D, Amicucci M, Li Pira G, Leone G, Bertaina V, Sinibaldi M, Di Cecca S, Guercio M, Abbaszadeh Z, Iaffaldano L, Gunetti M, Iacovelli S, Bugianesi R, Macchia S, Algeri M, Merli P, Galaverna F, Abbas R, Garganese MC, Villani MF, Colafati GS, Bonetti F, Rabusin M, Perruccio K, Folsi V, Quintarelli C, Locatelli F; Precision Medicine Team–IRCCS Ospedale Pediatrico Bambino Gesù. GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma. N Engl J Med. 2023 Apr 6;388(14):1284-1295. [https://doi.org/10.1056/nejmoa2210859 link to original article] [https://pubmed.ncbi.nlm.nih.gov/37018492/ PubMed] NCT03373097 | + | #'''GD2CAR01:''' Del Bufalo F, De Angelis B, Caruana I, Del Baldo G, De Ioris MA, Serra A, Mastronuzzi A, Cefalo MG, Pagliara D, Amicucci M, Li Pira G, Leone G, Bertaina V, Sinibaldi M, Di Cecca S, Guercio M, Abbaszadeh Z, Iaffaldano L, Gunetti M, Iacovelli S, Bugianesi R, Macchia S, Algeri M, Merli P, Galaverna F, Abbas R, Garganese MC, Villani MF, Colafati GS, Bonetti F, Rabusin M, Perruccio K, Folsi V, Quintarelli C, Locatelli F; Precision Medicine Team–IRCCS Ospedale Pediatrico Bambino Gesù. GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma. N Engl J Med. 2023 Apr 6;388(14):1284-1295. [https://doi.org/10.1056/nejmoa2210859 link to original article] [https://pubmed.ncbi.nlm.nih.gov/37018492/ PubMed] [https://clinicaltrials.gov/study/NCT03373097 NCT03373097] |
| − | [[Category: | + | [[Category:Anti-GD2 CAR T-cells]] |
[[Category:Intravenous medications]] | [[Category:Intravenous medications]] | ||
[[Category:Anti-GD2 cellular therapy]] | [[Category:Anti-GD2 cellular therapy]] | ||
| Line 12: | Line 12: | ||
[[Category:Neuroblastoma medications (investigational)]] | [[Category:Neuroblastoma medications (investigational)]] | ||
[[Category:Investigational drugs]] | [[Category:Investigational drugs]] | ||
| + | [[Category:Stub]] | ||
Latest revision as of 12:13, 4 July 2023
Mechanism of action
Anti-GD2 CAR T-cell
Preliminary data
Neuroblastoma
- GD2CAR01: Del Bufalo F, De Angelis B, Caruana I, Del Baldo G, De Ioris MA, Serra A, Mastronuzzi A, Cefalo MG, Pagliara D, Amicucci M, Li Pira G, Leone G, Bertaina V, Sinibaldi M, Di Cecca S, Guercio M, Abbaszadeh Z, Iaffaldano L, Gunetti M, Iacovelli S, Bugianesi R, Macchia S, Algeri M, Merli P, Galaverna F, Abbas R, Garganese MC, Villani MF, Colafati GS, Bonetti F, Rabusin M, Perruccio K, Folsi V, Quintarelli C, Locatelli F; Precision Medicine Team–IRCCS Ospedale Pediatrico Bambino Gesù. GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma. N Engl J Med. 2023 Apr 6;388(14):1284-1295. link to original article PubMed NCT03373097