Difference between revisions of "Anagrelide (Agrylin)"
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*[http://www.uptodate.com/contents/anagrelide-patient-drug-information Anagrelide (Agrylin) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/anagrelide-patient-drug-information Anagrelide (Agrylin) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/anagrelide-patient-drug-information Anagrelide (Agrylin) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/anagrelide-patient-drug-information Anagrelide (Agrylin) patient drug information (UpToDate)]</ref> | ||
| + | ==History of changes in PMDA indication== | ||
| + | *2014-09-26: Initial approval for the treatment of [[essential thrombocythemia]]. | ||
==Also known as== | ==Also known as== | ||
*'''Brand names:''' Agrylin, Xagrid | *'''Brand names:''' Agrylin, Xagrid | ||
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[[Category:FDA approved in 1997]] | [[Category:FDA approved in 1997]] | ||
[[Category:EMA approved in 2004]] | [[Category:EMA approved in 2004]] | ||
| + | [[Category:PMDA approved in 2014]] | ||
Revision as of 23:24, 9 June 2023
General information
Class/mechanism: Interferes with maturation of platelets from megakaryocytes, phosphodiesterase inhibitor.[1][2]
Route: PO
Extravasation: n/a
- Example of usage: Anagrelide (Agrylin) 0.5 mg PO four times per day or 1 mg PO twice per day, titrate to the lowest effective dose to maintain platelets below 600,000, maximum increase in dose of 0.5 mg/day every week (max dose: 10 mg/day, 2.5 mg in a single dose)
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, Medscape, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
Patient drug information
- Anagrelide (Agrylin) patient drug information (Chemocare)[3]
- Anagrelide (Agrylin) patient drug information (UpToDate)[4]
History of changes in PMDA indication
- 2014-09-26: Initial approval for the treatment of essential thrombocythemia.
Also known as
- Brand names: Agrylin, Xagrid