Difference between revisions of "Erlotinib (Tarceva)"
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(Created page with "==General information== Class/mechanism: <ref name="insert">[http://www.gene.com/gene/products/information/pdf/tarceva-prescribing.pdf Erlotinib (Tarceva) package insert]</ref><r...") |
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==General information== | ==General information== | ||
| − | Class/mechanism: <ref name="insert">[http://www.gene.com/gene/products/information/pdf/tarceva-prescribing.pdf Erlotinib (Tarceva) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/erlotinib.pdf Erlotinib (Tarceva) package insert (locally hosted backup)]</ref> | + | Class/mechanism: Small molecule tyrosine kinase inhibitor. Inhibits the intracellular phosphorylation activity of the epidermal growth factor receptor (EGFR) tyrosine kinase; may also have activity against other tyrosine kinase receptors. Exact mechanism of antitumor action is not fully characterized.<ref name="insert">[http://www.gene.com/gene/products/information/pdf/tarceva-prescribing.pdf Erlotinib (Tarceva) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/erlotinib.pdf Erlotinib (Tarceva) package insert (locally hosted backup)]</ref> |
| − | <br>Route: | + | <br>Route: PO |
| − | <br>Extravasation: | + | <br>Extravasation: n/a |
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the package insert<ref name="insert"></ref>. | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the package insert<ref name="insert"></ref>. | ||
==Patient drug information== | ==Patient drug information== | ||
| − | *[http://chemocare.com/bio/erlotinib. | + | *[http://chemocare.com/bio/erlotinib.asp Erlotinib (Tarceva) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/erlotinib.asp Erlotinib (Tarceva) patient drug information (Chemocare)]</ref> |
*[http://www.uptodate.com/contents/erlotinib-patient-drug-information Erlotinib (Tarceva) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/erlotinib-patient-drug-information Erlotinib (Tarceva) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/erlotinib-patient-drug-information Erlotinib (Tarceva) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/erlotinib-patient-drug-information Erlotinib (Tarceva) patient drug information (UpToDate)]</ref> | ||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 05:00, 11 January 2012
General information
Class/mechanism: Small molecule tyrosine kinase inhibitor. Inhibits the intracellular phosphorylation activity of the epidermal growth factor receptor (EGFR) tyrosine kinase; may also have activity against other tyrosine kinase receptors. Exact mechanism of antitumor action is not fully characterized.[1][2]
Route: PO
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the package insert[1].
Patient drug information
- Erlotinib (Tarceva) patient drug information (Chemocare)[3]
- Erlotinib (Tarceva) patient drug information (UpToDate)[4]