Difference between revisions of "Deferasirox (Exjade)"
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==General information== | ==General information== | ||
| − | Class/mechanism: Iron chelating agent; selective for the ferric form of iron: iron(III), Fe<sup>3+</sup>.<ref name="insert">[http://www.pharma.us.novartis.com/product/pi/pdf/exjade.pdf Deferasirox (Exjade) package insert]</ref><ref>[[ | + | Class/mechanism: Iron chelating agent; selective for the ferric form of iron: iron(III), Fe<sup>3+</sup>.<ref name="insert">[http://www.pharma.us.novartis.com/product/pi/pdf/exjade.pdf Deferasirox (Exjade) package insert]</ref><ref>[[:File:Deferasirox.pdf | Deferasirox (Exjade) package insert (locally hosted backup)]]</ref><ref>[http://www.exjade.com Exjade manufacturer's website]</ref> |
| − | <br>Route: PO | + | <br>Route: PO (powder); the PO tablet form of this medication is [[Deferasirox (Jadenu)]] |
<br>Extravasation: n/a | <br>Extravasation: n/a | ||
| − | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. | + | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> |
==Diseases for which it is used== | ==Diseases for which it is used== | ||
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*Brief patient counseling information can be found on [http://www.pharma.us.novartis.com/product/pi/pdf/exjade.pdf#page=21 Deferasirox (Exjade) package insert pages 21-22]<ref name="insert"></ref> | *Brief patient counseling information can be found on [http://www.pharma.us.novartis.com/product/pi/pdf/exjade.pdf#page=21 Deferasirox (Exjade) package insert pages 21-22]<ref name="insert"></ref> | ||
*[http://www.uptodate.com/contents/deferasirox-patient-drug-information Deferasirox (Exjade) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/deferasirox-patient-drug-information Deferasirox (Exjade) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/deferasirox-patient-drug-information Deferasirox (Exjade) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/deferasirox-patient-drug-information Deferasirox (Exjade) patient drug information (UpToDate)]</ref> | ||
| + | |||
| + | ==Also known as== | ||
| + | *'''Brand name:''' Exjade | ||
==References== | ==References== | ||
<references/> | <references/> | ||
| − | [[Category: | + | [[Category:Drugs]] |
| + | [[Category:Oral medications]] | ||
[[Category:Hematology medications]] | [[Category:Hematology medications]] | ||
[[Category:Chelators]] | [[Category:Chelators]] | ||
| + | |||
| + | [[Category:FDA approved in 2005]] | ||
| + | [[Category:Health Canada approved in 2006]] | ||
Latest revision as of 17:52, 29 March 2023
General information
Class/mechanism: Iron chelating agent; selective for the ferric form of iron: iron(III), Fe3+.[1][2][3]
Route: PO (powder); the PO tablet form of this medication is Deferasirox (Jadenu)
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
- Iron overload, secondary hemochromatosis
Patient drug information
- Brief patient counseling information can be found on Deferasirox (Exjade) package insert pages 21-22[1]
- Deferasirox (Exjade) patient drug information (UpToDate)[4]
Also known as
- Brand name: Exjade