Difference between revisions of "Vindesine (Eldisine)"
Jump to navigation
Jump to search
m |
m |
||
| Line 1: | Line 1: | ||
| − | |||
| − | |||
==General information== | ==General information== | ||
Class/mechanism: Vinca alkaloid, inhibits microtubule formation in the mitotic spindle, causing cell cycle arrest in metaphase.<ref name="insert">[http://www.bccancer.bc.ca/NR/rdonlyres/D6279B9B-2F71-4784-8AF8-D1452648635C/19507/Vindesinemonograph_3Nov07.pdf Vindesine (Eldisine) package insert]</ref><ref>[[Media:Vindesine.pdf | Vindesine (Eldisine) package insert (locally hosted backup)]]</ref> | Class/mechanism: Vinca alkaloid, inhibits microtubule formation in the mitotic spindle, causing cell cycle arrest in metaphase.<ref name="insert">[http://www.bccancer.bc.ca/NR/rdonlyres/D6279B9B-2F71-4784-8AF8-D1452648635C/19507/Vindesinemonograph_3Nov07.pdf Vindesine (Eldisine) package insert]</ref><ref>[[Media:Vindesine.pdf | Vindesine (Eldisine) package insert (locally hosted backup)]]</ref> | ||
| Line 9: | Line 7: | ||
==Diseases for which it is used== | ==Diseases for which it is used== | ||
| − | *[[ | + | *[[Burkitt lymphoma]] |
| + | *[[Diffuse large B-cell lymphoma]] | ||
*[[HIV-associated lymphoma]] | *[[HIV-associated lymphoma]] | ||
*[[Non-small cell lung cancer]] | *[[Non-small cell lung cancer]] | ||
| Line 17: | Line 16: | ||
*[http://www.genuspharma.com/assets/Vindesine-PIL.pdf Vindesine (Eldisine) patient information at Genus Pharmaceuticals]<ref>[http://www.genuspharma.com/assets/Vindesine-PIL.pdf Vindesine (Eldisine) patient information at Genus Pharmaceuticals]</ref> | *[http://www.genuspharma.com/assets/Vindesine-PIL.pdf Vindesine (Eldisine) patient information at Genus Pharmaceuticals]<ref>[http://www.genuspharma.com/assets/Vindesine-PIL.pdf Vindesine (Eldisine) patient information at Genus Pharmaceuticals]</ref> | ||
*[http://www.uptodate.com/contents/vindesine-patient-drug-information Vindesine (Eldisine) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/vindesine-patient-drug-information Vindesine (Eldisine) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/vindesine-patient-drug-information Vindesine (Eldisine) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/vindesine-patient-drug-information Vindesine (Eldisine) patient drug information (UpToDate)]</ref> | ||
| + | |||
| + | ==History of changes in FDA indication== | ||
| + | ''Not approved by the FDA. Approved for use in some countries e.g. Britain, South Africa.'' | ||
| + | |||
| + | ==Also known as== | ||
| + | Desacetylvinblastine amide, DAVA, DVA, Eldesine, Fildesin, or VDS. | ||
==References== | ==References== | ||
| Line 23: | Line 28: | ||
[[Category:Drug index]] | [[Category:Drug index]] | ||
[[Category:Chemotherapy]] | [[Category:Chemotherapy]] | ||
| + | [[Category:Intravenous chemotherapy]] | ||
| + | [[Category:Vesicant chemotherapy]] | ||
[[Category:Microtubule inhibitors]] | [[Category:Microtubule inhibitors]] | ||
[[Category:Vinca alkaloids]] | [[Category:Vinca alkaloids]] | ||
| − | [[Category: | + | [[Category:Burkitt lymphoma medications]] |
| + | [[Category:Diffuse large B-cell lymphoma medications]] | ||
[[Category:HIV-associated lymphoma medications]] | [[Category:HIV-associated lymphoma medications]] | ||
[[Category:Non-small cell lung cancer medications]] | [[Category:Non-small cell lung cancer medications]] | ||
Revision as of 02:55, 30 December 2014
General information
Class/mechanism: Vinca alkaloid, inhibits microtubule formation in the mitotic spindle, causing cell cycle arrest in metaphase.[1][2]
Route: IV
Extravasation: vesicant
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
Patient drug information
- Vindesine (Eldisine) patient information at Macmillan Cancer Support[3]
- Vindesine (Eldisine) patient information at Genus Pharmaceuticals[4]
- Vindesine (Eldisine) patient drug information (UpToDate)[5]
History of changes in FDA indication
Not approved by the FDA. Approved for use in some countries e.g. Britain, South Africa.
Also known as
Desacetylvinblastine amide, DAVA, DVA, Eldesine, Fildesin, or VDS.
References
- ↑ 1.0 1.1 Vindesine (Eldisine) package insert
- ↑ Vindesine (Eldisine) package insert (locally hosted backup)
- ↑ Vindesine (Eldisine) patient information at Macmillan Cancer Support
- ↑ Vindesine (Eldisine) patient information at Genus Pharmaceuticals
- ↑ Vindesine (Eldisine) patient drug information (UpToDate)