Difference between revisions of "Dutasteride (Avodart)"
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(Created page with "==General information== Class/mechanism: <ref name="insert">[http://us.gsk.com/products/assets/us_avodart.pdf Dutasteride (Avodart) package insert]</ref><ref>[http://hemonc.org/d...") |
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==General information== | ==General information== | ||
| − | Class/mechanism: <ref name="insert">[http://us.gsk.com/products/assets/us_avodart.pdf Dutasteride (Avodart) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/SHORTER MEDICATION NAME.pdf Dutasteride (Avodart) package insert (locally hosted backup)]</ref> | + | Class/mechanism: 5 alpha-reductase, inhibits conversion of testosterone to dihydrotestosterone (DHT). Competitively inhibits type 1 and 2 5 alpha-reductase isoenzymes by forming a stable enzyme complex with them.<ref name="insert">[http://us.gsk.com/products/assets/us_avodart.pdf Dutasteride (Avodart) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/SHORTER MEDICATION NAME.pdf Dutasteride (Avodart) package insert (locally hosted backup)]</ref> |
| − | <br>Route: | + | <br>Route: PO |
| − | <br>Extravasation: | + | <br>Extravasation: n/a |
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the package insert<ref name="insert"></ref>. | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the package insert<ref name="insert"></ref>. | ||
Revision as of 16:01, 24 December 2011
General information
Class/mechanism: 5 alpha-reductase, inhibits conversion of testosterone to dihydrotestosterone (DHT). Competitively inhibits type 1 and 2 5 alpha-reductase isoenzymes by forming a stable enzyme complex with them.[1][2]
Route: PO
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the package insert[1].
Patient drug information
- MEDICATION NAME-patient-drug-information Dutasteride (Avodart) patient drug information (UpToDate)[3]